๐ What is Gelatinous Drop-like Dystrophy (GDLD)?
Gelatinous Drop-like Dystrophy (GDLD) is a rare inherited corneal dystrophy
characterized by the formation of gelatinous, cyst-like opacities on the corneal surface.
๐ Key Features
- Usually appears in early childhood, with mulberry-like elevated lesions beneath the epithelium
- Caused by amyloid protein deposition in the superficial stroma
- Progressive vision loss typically begins before age 20
๐งฌ Pathology and Prognosis
- Amyloid accumulates and spreads throughout the cornea
- Corneal transplantation is often required
- However, the disease has a high recurrence rate,
even after successful transplantation - Without treatment, total corneal opacity can occur
โ Summary
- Extremely rare inherited corneal disorder
- Gelatinous, mulberry-like amyloid opacities
- Early-onset vision loss, often requiring corneal transplantation
- High rate of recurrence even after surgery
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