👁 What is Fleck Corneal Dystrophy (FCD)?
Fleck Corneal Dystrophy (FCD) is a rare, inherited corneal condition
in which small, freckle-like grayish opacities appear throughout the corneal stroma.
🧬 Key Characteristics
- Opacities are confined to the stroma, not affecting the epithelium
- They are scattered throughout all stromal layers, often asymmetrically
- Usually bilateral, but can also appear unilaterally
- No associated pain, redness, or foreign body sensation
- Lesions may become more noticeable with age
🔍 Symptoms and Diagnosis
- Most patients are asymptomatic, with normal vision
- Occasionally, patients may notice mild blurred vision
- Typically discovered incidentally during slit-lamp examination
🧬 Cause
- The exact gene is not yet identified,
but the condition is believed to be related to lysosomal metabolism disorders - Deposits are thought to be lipid or glycosaminoglycan materials
- Histologically shows PAS-positive and Sudan-positive granules
💊 Treatment
📌 Because vision is usually unaffected, and there are no painful symptoms,
📌 No medical or surgical treatment is required.
📌 Regular observation is sufficient.
✅ Summary
- Rare genetic corneal dystrophy
- Freckle-like stromal opacities, usually harmless
- No vision loss, no discomfort, no treatment needed
- Just routine follow-up is recommended
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