Contents
Disease&Treatment/Cornea&Ocular surfaces

Posterior Amorphous Stromal Dystrophy (PASD), cause treatment genetics onset symptom

by eye_doc 2025. 4. 13.

👁 What is Posterior Amorphous Stromal Dystrophy (PASD)?

Posterior Amorphous Stromal Dystrophy (PASD) is a rare, inherited corneal condition
characterized by irregular, grayish, wave-like opacities in the posterior corneal stroma.


🧬 Inheritance and Onset

  • Often present at birth or early childhood
  • Passed down through autosomal dominant inheritance

 


🔍 Key Features

  • Opacities are limited to the posterior central corneal stroma
  • Appear as thin, gray, sheet-like hazes in a non-uniform pattern
  • Normal stromal areas remain between the hazy regions
  • Affected corneas may become thinner and flatter, causing hyperopia (farsightedness)
  • Occasionally associated with iris abnormalities, though visual function is usually preserved

💊 Is Treatment Needed?

📌 Since vision is typically not significantly affected and the condition is non-progressive,
no treatment is usually required.


✅ Summary

  • Rare, autosomal dominant inherited disorder
  • Wave-like stromal opacities in the posterior cornea
  • Can cause flattening of the cornea and hyperopia
  • Generally harmless, with no need for treatment

Comments