Coats' disease, Coats' disease causes treatment symptoms tests prognosis blindness

 

👁 Coats' Disease – A Progressive Pediatric Retinal Vascular Disorder

Coats' disease is a rare, typically unilateral pediatric retinal disorder
characterized by retinal telangiectasia, lipid exudation, and exudative retinal detachment.
It most commonly presents in young boys (<10 years) and may lead to vision loss or enucleation.

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✅ Clinical Summary

FeatureDescription

Onset	Mean age ~5 years, 75% male
Eye Involvement	Unilateral in 95%
Symptoms	Decreased vision, leukocoria, strabismus
Fundus	Telangiectatic vessels, yellow-white exudates
Complication	Total RD, NVG, Phthisis
Cause	Idiopathic, possible NDP gene mutation
Diagnostic Tools	Fundoscopy, FAG, OCT

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✅ Treatment Overview

StageTreatment

Early	Observation, laser photocoagulation
Moderate	Cryotherapy, anti-VEGF
Advanced	PPV, retinal detachment drainage
With NVG	Management of glaucoma
End-stage	Enucleation in phthisis