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๐Ÿ‘ Retinal Changes in Pregnancy – What’s New, What Worsens, and What Tests Are Safe?

Pregnancy affects the eye not only through hypertensive disorders like pre-eclampsia,
but also by triggering new retinal diseases or exacerbating pre-existing ones.
Additionally, diagnostic procedures must be evaluated for fetal safety.

 

 


โœ… Retinal Diseases Newly Triggered During Pregnancy

DiseaseDetails
CSC Unilateral, 3rd trimester, resolves postpartum, subretinal exudates common
Serous RD in DIC Self-limiting, minor pigment changes after resolution
Uveal Melanoma Hormone-driven melanin increase, malignant potential uncertain

โœ… Pregnancy-Induced Changes in Existing Conditions

DiseasePregnancy Impact
Diabetic Retinopathy (DR) Worsens with poor glycemic control, DME may increase
Toxoplasmosis No transmission risk to fetus from maternal ocular lesions
VKH Exacerbation in 1st trimester
Behcet’s Disease Worsens postpartum
High Myopia No added risk of retinal detachment during delivery
Choroidal Hemangioma May grow rapidly during pregnancy
RPE dystrophy Can worsen suddenly during pregnancy

โœ… Diagnostic Test Safety in Pregnancy

TestSafety
Fluorescein Angiography (FAG) Crosses placenta → use only if essential
ICG Angiography Does not cross placenta → safe
Photodynamic Therapy (PDT) Avoid – verteporfin safety in pregnancy unknown
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