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What is Corneal Lipid Degeneration?

Corneal Lipid Degeneration refers to the accumulation of lipids (fats) in the cornea,
which can lead to corneal opacities. It is classified into:

  • Primary (idiopathic)
  • Secondary (acquired)

 


๐Ÿ”น Primary Lipid Degeneration

  • Extremely rare; no identifiable underlying cause
  • Occurs without corneal neovascularization
  • Lipids deposit in both central and peripheral stroma
  • Blood lipid levels are typically normal
  • Seen in deep stroma and Descemet’s membrane
  • Corneal transplantation may be considered,
    → but prognosis is often poor

 


๐Ÿ”ธ Secondary Lipid Degeneration

  • More common
  • Follows conditions that induce corneal neovascularization, such as:
    • Interstitial keratitis
    • Corneal trauma, ulcers, or edema
  • Lipids leak from abnormal vessels and accumulate in the cornea
  • Can appear:
    • As disc-shaped deposits in areas of active inflammation
    • As fan-shaped patterns near old, inactive vessels
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ยซ   2025/06   ยป
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